Stevens-Johnson syndrome induced by sodium valproate monotherapy

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Stevens - Johnson Syndrome Induced by Sodium Valproate

A case of Stevens-Johnson syndrome (SJS) following treatment with sodium valproate is presented. A 55-year-old male suffering from manic episode was treated with sodium valproate in addition to haloperidol and trihexiphenidyl. After two weeks he developed cutaneous manifestations of SJS. He was treated with systemic steroids, antihistamines and topical calamine lotion and recovered after a few ...

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Stevens-Johnson syndrome (SJS) is an acute mucocutaneous eruption nosologically related to erythema multiforme (EM) and toxic epidermal necrolysis (TEN). Medications are the most common triggering factors for SJS, with anticonvulsants, sulfonamides, penicillins, allopurinol, and nonsteroidal anti-inflammatory drugs (NSAIDs) most commonly implicated. SJS is very rarely associated with tetracycli...

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Stevens-Johnson syndrome (SJS) is a mucocutaneous disorder induced by an immune-complex-mediated hypersensitivity reaction. Nearly half of cases are caused by a reaction to drugs or appear during viral infections and malignancies. A very few cases are caused by a bacterial infection (Streptococcus) or Mycoplasma pneumoniae. Graft versus host disease is another well-established cause, independen...

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Li-Ping Zou *, Chang-Hong Ding , Zhen-Jiang Song , Xiao-Feng Li c Department of Pediatrics, Chinese PLA General Hospital (No. 301 Hospital), Beijing, China Department of Neurology, Beijing Children’s Hospital, The Capital Medical University, Beijing, China Department of Cardiac Surgery, Beijing Children’s Hospital, The Capital Medical University, Beijing, China

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ژورنال

عنوان ژورنال: International Journal of Critical Illness and Injury Science

سال: 2012

ISSN: 2229-5151

DOI: 10.4103/2229-5151.94904